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Summary

Brain-computer interface (BCI) research deals with establishing communication pathways between the brain and external devices where such pathways do not otherwise exist. Throughout the world, such research is surprisingly extensive and expanding. BCI research is rapidly approaching a level of first-generation medical practice for use by individuals whose neural pathways are damaged, and use of BCI technologies is accelerating rapidly in nonmedical arenas of commerce as well, particularly in the gaming, automotive, and robotics industries. The technologies used for BCI purposes are cutting-edge, enabling, and synergistic in many interrelated arenas, including signal processing, neural tissue engineering, multiscale modeling, systems integration, and robotics.

Author Biography

Dr. Theodore W. Berger (Panel Chair) is the David Packard Professor of Engineering, Professor of Biomedical Engineering and Neuroscience, and Director of the Center for Neural Engineering at the University of Southern California. He received his PhD from Harvard University in 1976; his thesis work received the James McKeen Cattell Award from the New York Academy of Sciences. He conducted postdoctoral research at the University of California, Irvine, from 1977-1978 and was an Alfred P. Sloan Foundation Fellow at the Salk Institute from 1978-1979. Dr. Berger joined the Departments of Neuroscience and Psychiatry at the University of Pittsburgh in 1979, being promoted to full professor in 1987. During that time, he received a McKnight Foundation Scholar Award, twice received an NIMH Research Scientist Development Award, and was elected a Fellow of the American Association for the Advancement of Science. Since 1992, he has been Professor of Biomedical Engineering and Neurobiology at the University of Southern California, and was appointed the David Packard Chair of Engineering in 2003. While at USC, Dr. Berger has received an NIMH Senior Scientist Award, was elected a Fellow of the American Institute for Medical and Biological Engineering in 1998, received a Person of the Year "Impact Award" by the AARP in 2004 for his work on neural prostheses, was a National Academy of Sciences International Scientist Lecturer in 2003, and an IEEE Distinguished Lecturer in 2004-2005. Dr. Berger was elected a Senior Member of the IEEE in 2005, and received a "Great Minds, Great Ideas" award from the EE Times in the same year. Dr. Berger is currently chair of an NIH study section that evaluates grants related to clinical neurophysiological, medical devices, and neural prosthetics. Dr. Berger became Director of the Center for Neural Engineering in 1997, an organization that helps to unite USC faculty with cross-disciplinary interests in neuroscience, engineering, and medicine. He has published over 200 journal articles and book chapters, and is the coeditor of a book recently published by the MIT Press: Toward Replacement Parts for the Brain: Implantable Biomimetic Electronics as Neural Prostheses.Dr. Berger's research focuses on electrophysiological and theoretical studies of hippocampal neurons and circuits for the purpose of developing neural prostheses and biological-based pattern recognizers.

Table of Contents

Acknowledgmentsp. v
Forewordp. ix
List of Figuresp. xv
List of Tablesp. xvii
Prefacep. xix
Executive Summaryp. xxvii
Introductionp. 1
Background and Scopep. 1
Methodologyp. 2
Overview of the Reportp. 5
Sensor Technologyp. 7
Introductionp. 7
BCI Sensor World Overviewp. 8
Major Types of Sensors for BCI Technologyp. 9
Major Challenges for Producing BCI Sensorsp. 24
Summary and Conclusionsp. 25
Referencesp. 26
The Biotic-Abiotic Interfacep. 31
Introductionp. 31
BCI Abiotic-Biotic Interface World Overviewp. 33
Strategies under Development to Improve Electrode Performancep. 41
Summary and Conclusionsp. 42
Referencesp. 43
BMI/BCI Modeling and Signal Processingp. 47
Introductionp. 47
Multimicroelectrode Array Techniquesp. 48
EEG/ECoG Recordingsp. 54
Summary and Conclusionsp. 58
Referencesp. 60
Hardware Implementationp. 65
Introduction: Restoring Movement in Paralysis Patientsp. 65
Different Approaches to BCI Research Worldwidep. 67
Original Feasibility Demonstrations for Brain-Controlled Roboticsp. 69
Brain Control of Multiple-Output Functionsp. 72
Biomimetic Robot Research at the Scuola Superiore Sant' Annap. 74
Referencesp. 78
Functional Electrical Stimulation and Rehabilitation Applications of BCIsp. 81
Overview of Functional Electrical Stimulationp. 81
FES Applications of BCI Technology around the Worldp. 84
How Different Types of BCI Command Signals can be Applied to FESp. 88
Application Areas of BCI-Controlled FES Systemsp. 89
Practical Considerationsp. 93
Referencesp. 93
Noninvasive Communication Systemsp. 95
Introductionp. 95
Slow Cortical Potentialsp. 96
Steady-State Evoked Potentialsp. 98
Online Evaluationsp. 102
Prospects for Practical BCI Communication Systemsp. 103
Summary and Conclusionsp. 104
Referencesp. 105
Cognitive and Emotional Neuroprosthesesp. 109
Introductionp. 109
Volitional Prosthesesp. 109
Emotional Computers and Robotsp. 112
Memory Prosthesesp. 113
Neurofeedbackp. 118
Summary and Conclusionsp. 121
Referencesp. 122
Research Organization-Funding, Translation-Commercialization, and Education-Training Issuesp. 125
BCI Research Organization and Fundingp. 125
Funding and Funding Mechanismsp. 133
Translation-Commercializationp. 134
Training-Educationp. 139
Referencesp. 140
Appendices
Biographies of Panelists and Delegation Membersp. 141
Site Reports-Europep. 149
Aalborg Universityp. 149
Berlin Brain-Computer Interfacep. 153
Commissariat a l'Energie Atomique (CEA)p. 161
CNRS/College de France Physiology of Perception and Action Laboratoryp. 164
European Commission, Research Directorate Generalp. 168
Graz University of Technologyp. 170
Guger Technologies OEG, "g.tec"p. 174
Max Planck Institute of Biochemistryp. 178
Natural and Medical Sciences Institute at the University of Tubingen and Retina Implant GmbHp. 184
Multi Channel Systems (MCS)p. 191
The Santa Lucia Foundation Laboratory of Neuroelectrical Imaging and Brain-Computer Interfacep. 196
Polo Sant' Anna Valderap. 202
Swiss Federal Institute of Technology, Lausannep. 205
University of Edinburghp. 208
University of Freiburgp. 210
University of Oxfordp. 216
University of Tubingenp. 221
Site Reports-Asiap. 225
Advanced Telecommunications Research Institute Internationalp. 225
Huazhong University of Science and Technologyp. 232
NTT Communication Science Laboratoriesp. 236
RIKEN Brain Science Institutep. 244
Shanghai Institute of Brain Functional Genomicsp. 248
Shanghai Jiao-Tong Universityp. 252
Tsinghua University Department of Biomedical Engineeringp. 258
Tsinghua University Institute of Microelectronicsp. 265
Waseda Universityp. 270
Wuhan Universityp. 274
Glossaryp. 279
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