Summary
From the reviews of the First Edition . . . "An excellent text . . . will no doubt provide the benchmark for comparative works for many years." -Journal of the American Chemical Society "A resounding success . . . the definitive current summaries on their respective subjects." -Synthesis Since this important work was first published in 1993, the field of catalytic asymmetric synthesis has grown explosively, spawning effective new methods for obtaining enantiomerically pure compounds on a large scale and stimulating new applications in diverse fields-from medicine to materials science. Catalytic Asymmetric Synthesis, Second Edition addresses these rapid changes through new or substantially revised contributions from highly recognized world leaders in the field. It presents detailed accounts of the most important catalytic asymmetric reactions known today, discusses recent advances, and retains from the previous edition essential and intriguing information on the initial development of certain processes. An excellent working resource for academic researchers and industrial chemists alike, the Second Edition features: Contributions from Noyori, Sharpless, Kagan, Trost, Overman, Shibasaki, Doyle, Okamoto, Bolm, Carreira, and many other internationally renowned authorities New chapters on asymmetric carbometallations, asymmetric amplification and autocatalysis, and asymmetric polymerization Extended coverage of asymmetric carbene reactions, including asymmetric intramolecular carbene insertion to C-H bonds as well as asymmetric dihydroxylation and aminohydroxylation Extended coverage of asymmetric carbon-carbon bond-forming reactions and applications An appendix listing all chiral ligands in the book
Author Biography
<b>IWAO OJIMA, PhD</b>, is Distinguished Professor of Chemistry at the State University of New York at Stony Brook. He is also an Arthur C. Cope Scholar (ACS), a Guggenheim Fellow, and a Fellow of the American Association for the Advancement of Science.
Table of Contents
| Preface |
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ix | |
| Preface to the First Edition |
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xi | |
| Contributors |
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xiii | |
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1 | (110) |
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Asymmetric Hydrosilylation and Related Reactions |
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111 | (34) |
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Asymmetric Isomerization of Allylamines |
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145 | (20) |
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162 | (3) |
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Asymmetric Carbometallations |
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165 | (26) |
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Asymmetric Addition and Insertion Reactions of Catalytically-Generated Metal Carbenes |
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191 | (38) |
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Asymmetric Oxidations and Related Reactions |
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229 | (200) |
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Catalytic Asymmetric Epoxidation of Allylic Alcohols |
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231 | (56) |
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281 | (6) |
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Asymmetric Epoxidation of Unfunctionalized Olefins and Related Reactions |
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287 | (40) |
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Asymmetric Oxidation of Sulfides |
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327 | (30) |
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Catalytic Asymmetric Dihydroxylation---Discovery and Development |
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357 | (42) |
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Recent Advances in Asymmetric Dihydroxylation and Aminohydroxylation |
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399 | (30) |
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Asymmetric Carbonylations |
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429 | (36) |
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Asymmetric Carbon--Carbon Bond-Forming Reactions |
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465 | (234) |
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Asymmetric Cycloaddition Reactions |
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467 | (26) |
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Asymmetric Aldol Reactions---Discovery and Development |
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493 | (50) |
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Recent Advances in Asymmetric Aldol Addition Reactions |
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513 | (30) |
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543 | (26) |
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Asymmetric Michael Reactions |
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569 | (24) |
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Asymmetric Allylic Alkylation Reactions |
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593 | (58) |
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Asymmetric Cross-Coupling Reactions |
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651 | (24) |
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Asymmetric Intramolecular Heck Reactions |
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675 | (24) |
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Asymmetric Amplification and Autocatalysis |
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699 | (28) |
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Asymmetric Phase-Transfer Reactions |
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727 | (30) |
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Asymmetric Polymerization |
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757 | (40) |
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| Epilogue |
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797 | (4) |
| Appendix---List of Chiral Ligands |
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801 | (56) |
| Index |
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857 | |