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Summary

From the reviews of the First Edition . . . "An excellent text . . . will no doubt provide the benchmark for comparative works for many years." -Journal of the American Chemical Society "A resounding success . . . the definitive current summaries on their respective subjects." -Synthesis Since this important work was first published in 1993, the field of catalytic asymmetric synthesis has grown explosively, spawning effective new methods for obtaining enantiomerically pure compounds on a large scale and stimulating new applications in diverse fields-from medicine to materials science. Catalytic Asymmetric Synthesis, Second Edition addresses these rapid changes through new or substantially revised contributions from highly recognized world leaders in the field. It presents detailed accounts of the most important catalytic asymmetric reactions known today, discusses recent advances, and retains from the previous edition essential and intriguing information on the initial development of certain processes. An excellent working resource for academic researchers and industrial chemists alike, the Second Edition features: Contributions from Noyori, Sharpless, Kagan, Trost, Overman, Shibasaki, Doyle, Okamoto, Bolm, Carreira, and many other internationally renowned authorities New chapters on asymmetric carbometallations, asymmetric amplification and autocatalysis, and asymmetric polymerization Extended coverage of asymmetric carbene reactions, including asymmetric intramolecular carbene insertion to C-H bonds as well as asymmetric dihydroxylation and aminohydroxylation Extended coverage of asymmetric carbon-carbon bond-forming reactions and applications An appendix listing all chiral ligands in the book

Author Biography

<b>IWAO OJIMA, PhD</b>, is Distinguished Professor of Chemistry at the State University of New York at Stony Brook. He is also an Arthur C. Cope Scholar (ACS), a Guggenheim Fellow, and a Fellow of the American Association for the Advancement of Science.

Table of Contents

Preface ix
Preface to the First Edition xi
Contributors xiii
Asymmetric Hydrogenation
1(110)
Takeshi Ohkuma
Masato Kitamura
Ryoji Noyori
Asymmetric Hydrosilylation and Related Reactions
111(34)
Hisao Nishiyama
Kenji Itoh
Asymmetric Isomerization of Allylamines
145(20)
Susumu Akutagawa
Kazuhide Tani
Addendum---1999
162(3)
Xin Wen
Iwao Ojima
Asymmetric Carbometallations
165(26)
Ei-ichi Negishi
Asymmetric Addition and Insertion Reactions of Catalytically-Generated Metal Carbenes
191(38)
Michael P. Doyle
Asymmetric Oxidations and Related Reactions
229(200)
Catalytic Asymmetric Epoxidation of Allylic Alcohols
231(56)
Roy A. Johnson
K. Barry Sharpless
Addendum---1999
281(6)
Xin Wen
Iwao Ojima
Asymmetric Epoxidation of Unfunctionalized Olefins and Related Reactions
287(40)
Tsutomu Katsuki
Asymmetric Oxidation of Sulfides
327(30)
Henri B. Kagan
Catalytic Asymmetric Dihydroxylation---Discovery and Development
357(42)
Roy A. Johnson
K. Barry Sharpless
Recent Advances in Asymmetric Dihydroxylation and Aminohydroxylation
399(30)
Carsten Bolm
Jens P. Hildebrand
Kilian Muniz
Asymmetric Carbonylations
429(36)
Kyoko Nozaki
Iwao Ojima
Asymmetric Carbon--Carbon Bond-Forming Reactions
465(234)
Asymmetric Cycloaddition Reactions
467(26)
Keiji Maruoka
Asymmetric Aldol Reactions---Discovery and Development
493(50)
Masaya Sawamura
Yoshihiko Ito
Recent Advances in Asymmetric Aldol Addition Reactions
513(30)
Erick M. Carreira
Asymmetric Ene Reactions
543(26)
Koichi Mikami
Takeshi Nakai
Asymmetric Michael Reactions
569(24)
Motomu Kanai
Masakatsu Shibasaki
Asymmetric Allylic Alkylation Reactions
593(58)
Barry M. Trost
Chulbom Lee
Asymmetric Cross-Coupling Reactions
651(24)
Masamichi Ogasawara
Tamio Hayashi
Asymmetric Intramolecular Heck Reactions
675(24)
Yariv Donde
Larry E. Overman
Asymmetric Amplification and Autocatalysis
699(28)
Kenso Soai
Takanori Shibata
Asymmetric Phase-Transfer Reactions
727(30)
Martin J. O'Donnell
Asymmetric Polymerization
757(40)
Yoshio Okamoto
Tamaki Nakano
Epilogue 797(4)
Appendix---List of Chiral Ligands 801(56)
Index 857

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