Clinical Dilemmas in Inflammatory Bowel Disease

Evidence-based guidance to answer more than 60 controversial clinical questions on inflammatory bowel diseaseClinical Dilemmas in Inflammatory Bowel Disease is a practical handbook providing quick but detailed answers to the questions and challenges that you are faced with daily in the clinical setting.Each short chapter addresses a different topic and provides evidence-based guidance on subjects ranging from optimising current management through to special management problems and novel treatments.This book is suitable for all medical professionals involved in the care of patients with IBD: established and trainee gastroenterologists, colorectal surgeons, pathologists, radiologists, specialist nurses, pharmacists, dieticians and counsellors

List of Contributors. Preface.. Part 1 Investigating IBD in the 21st Century. 1 Capsule endoscopy: do we need it (Joel E D Mawdsley & Mark Appleyard). 2 Pathology reports - pitfalls for the unwary (Wilfred Weinstein). 3 Non-invasive diagnosis and assessment (Alex J Di Mambro, Ana Terlevich & Chris Probert). 4 What is the best way to image perianal Crohn's disease (Vikram A Sahni & Alison McLean). 5 Surveillance colonoscopy in UC: alternatives and ways to improve outcome (Mark Lust & William Connell). 6 Abnormal liver tests - what should we do about them (Richard Marley & Abid Suddle). Part 2 Medical Treatment: Making the Most of What We've Got. 5-ASA drugs. 7 Is monitoring necessary (Rakesh Shah & Alastair Forbes). 8 Do they have a role in Crohn's disease (Vikrant Sibartie & Brian Feagan). Steroids. 9 Steroids in Crohn's: are they obsolete (David Rampton). Antibiotics for Crohn's disease. 10 Antibiotics: which, when and for how long (Alex Kent & Jean-Fr_d_ric Colombel). 11 Mycobacterium avium paratuberculosis in Crohn's disease: player or spectator (Geoff Smith & Fergus Shanahan). Immunomodulators. 12 TPMT testing: is it essential (Azhar Ansari & Jeremy D Sanderson). 13 6-Mercaptopurine or azathioprine (Dermot McGovern & Simon Travis). 14 Thiopurines: how long should we use them for (Alexandra Daley & Marc L_mann). 15 Making the most of methotrexate (Emma Greig, John Keohane & Brian Feagan). 16 Cyclosporine: balancing risk and benefit (Helena Deeney & Barney Hawthorne). Infliximab. 17 Contraindications - absolute or relative (Rakesh Chaudhary & Subrata Ghosh). 18 How can we prevent tuberculosis (Sasha Beresford & David Rampton). 19 Dealing with infusion reactions (Gert Van Assche, S_verine Vermeire & Paul Rutgeerts). 20 Use in ulcerative colitis (Sreedhar Subramanian & Jonathan Rhodes). 21 Infliximab and surgery: health or hazard (David Rampton). Nutritional therapy for Crohn's disease. 22 Nutritional therapy for Crohn's disease: is it for adults (Donald R Duerksen & Charles N Bernstein). Part 3 Medical Treatment: What's Round the Corner?. 23 Trials and tribulations - interpreting clinical trials in IBD (Elizabeth Carty & David Rampton). 24 Genetics - clinical and therapeutic applications (Mark Tremelling & Miles Parkes). 25 Probiotics - separating science from snakeoil (Fergus Shanahan & John Keohane). 26 Worms (David Grunkemeier & R Balfour Sartor). 27 Smoking and nicotine - poison for Crohn's, potion for colitis (Brian Bressler & A Hillary Steinhart). 28 Heparin (Ailsa Hart & Stuart Bloom). 29 Leukocytapheresis: filtering out the facts (Peter Irving & David Rampton). 30 Appendectomy for ulcerative colitis - a therapeutic option (Richard Makins & Graham Radford-Smith). 31 Biologic treatments in IBD (Raymond D'Souza & James Lindsay). 32 Stem cell transplantation for IBD (Paul Fortun & Christopher Hawkey). 33 Complementary and alternative therapy - the way forward or a step back (Louise Langmead & David Rampton). Part 4 Common Clinical Challenges: Beyond the Text Book. 34 Functional problems (Eamonn Quigley). 35 Psychological stress: something to worry about (Joel E D Mawdsley & David Rampton). 36 Drugs to avoid (Paul Collins & Jonathan Rhodes). 37 NSAIDs and COX-2 selective agents: cause or cure of pain in IBD (Ingvar Bjarnason & David Scott). 38 Iron replacement - is it safe