Triplet Pregnancies and Their Consequences

by ;
Edition: 1st
Format: Hardcover
Pub. Date: 2002-10-16
Publisher(s): CRC Press
List Price: $170.00

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Summary

With the advent of assisted reproduction, the frequency of multiple births has grown dramatically. Though once rare, triplet births are now seen surprisingly often. Whereas twins have been the object of much important study, virtually nothing has been published focusing solely on triplets, until now.Triplet Pregnancies and their Consequences is unique: it is the first systematic, scientific review of the study of triplets. Covering the range of issues and complications possible in triplet pregnancies, the book includes ten distinct sections devoted to prenatal, intrapartum, and postnatal aspects of these pregnancies. It contains an analysis of a unique database of more than 3000 triplet pregnancies provided by Matria Healthcare of Marietta, Georgia. This is the first time there have been sufficient numbers of triplets in a data set to truly understand some of the unique biological circumstances associated with triplets.Topics include:· Epidemiology and biology - including unique matched analyses of the entire French IVF registry· Prenatal diagnosis with special attention to chorionicity· Antepartum considerations with broad perspectives on treatment of preterm labor· Delivery considerations· The Matria Analysis - the largest triplet database in the world· Short-term outcomes with special attention to low birth weight· Long-term outcomes focusing on cerebral palsy and school performanceTriplet Pregnancies and their Consequences is the first of its kind, a true landmark text. It will be indispensable to all healthcare providers dealing with the worldwide "epidemic" of iatrogenic triplets.

Table of Contents

List of principal contributors
ix
Preface xiii
Foreword by Professor The Lord Patel xv
Foreword xvii
John J. Sciarra
List of illustrations
xix
I. Epidemiology and biology 1(54)
The frequency of triplet gestation
3(6)
L. G. Keith
J. E. Fajardo
J. J. Oleszczuk
Spontaneous and induced triplets
9(8)
I. Blickstein
Triplet zygosity and chorionicity
17(16)
G. A. Machin
Ultrasound evaluation of unusual triplet gestations
33(12)
I. E. Timor-Tritsch
A. Monteagudo
A. Rebarber
Triplet pregnancies from French IVF Centers: 1986--98
45(10)
E. Papiernik
J. de Mouzon
II. Prenatal diagnosis 55(66)
Early ultrasound and triplet pregnancy
57(8)
S. T. Chasen
D. W. Skupski
Screening for chromosomal abnormalities in triplet and high-order multiple pregnancy
65(8)
R. Maymon
A. Herman
Amniocentesis and chorionic villus sampling in triplet pregnancies
73(12)
R. A. Greene
R. J. Wapner
M. I. Evans
Pitfalls and caveats in ultrasound assessment of triplet pregnancies
85(22)
A. Kurjak
M. Kos
N. Vecek
Fetal surveillance and timing of delivery in triplet gestations
107(14)
R. B. Newman
III. Antepartum considerations 121(124)
A. Preterm labor
Routine antepartum care for triplets
123(10)
I. Blickstein
Prediction of preterm triplet birth by clinical assessment
133(16)
B. Arabin
A. Merien
J. van Eyck
Tocolysis in triplet gestation
149(26)
S. Rodts-Palenik
J. C. Morrison
Aggressive proactive management of triplet preterm labor
175(6)
J. P. Elliott
Subcutaneous terbutaline therapy in triplet gestation
181(22)
F. Lam
P. Gill
Aggressive versus conservative management in triplet pregnancies
203(12)
Y. Oyelese
S. Poggi
J. V. Collea
B. Maternal complications
Maternal complications associated with triplet pregnancies
215(10)
V. R. Klein
Hypertensive disorders during triplet gestations
225(6)
M. Smith-Levitin
C. Fetal complications
Complications of monochorionicity in triplet gestations
231(8)
G. A. Machin
Fetal growth in triplet pregnancies
239(6)
I. Blickstein
IV. Delivery/birth considerations 245(20)
Delivery route in triplets
247(12)
R. B. Kalish
D. W. Skupski
Breastfeeding triplets: personal reflections
259(6)
J. L. Bleyl
V. The Matria database 265(28)
The Matria triplet database: 1988--2000
267(26)
I. Blickstein
D. L. Jacques
VI. Short-term outcomes 293(26)
Neonatal outcomes and their long-term consequences in triplets
295(12)
E. S. Shinwell
S. Even-Tov Friedman
Mortality and morbidity of the extremely preterm infant
307(12)
R.-A. deRegnier
VII. Long-term outcomes 319(64)
Cerebral palsy in triplets
321(12)
B. Petterson
L. Watson
J. J. Kurinczuk
School performance for triplets
333(10)
B. Alin Akerman
Perinatal management of the triplet family
343(12)
K. S. Collopy
Bereavement in higher-order multiple pregnancy
355(6)
E. Bryan
J. Denton
Familial and psychological reaction in triplet families
361(10)
J. L. Bleyl
Competing factors leading to iatrogenic multiple pregnancies
371(12)
S. C. Klock
VIII. Preventive measures 383(36)
Maternal nutrition: an evidence-based approach for triplet gestations
385(16)
J. J. Oleszczuk
A. K. Oleszczuk
K. Shelke
L. G. Keith
Avoiding triplet pregnancy in assisted reproduction
401(10)
J. D. Fisch
P. Uzelac
G. Sher
Selective reduction in triplet pregnancies
411(8)
M. I. Evans
D. W. Britt
I. E. Zador
R. J. Wapner
IX. Miscellaneous 419(44)
Ethical issues in caring for triplet pregnancies
421(8)
F. A. Chervenak
L. B. McCullough
Cost-minimization analysis of one-, two- and three-embryo transfers in IVF
429(8)
C. Jones
R. Ward
Economic implications of multiple births
437(6)
J. Henderson
S. Petrou
A mother of quads speaks
443(20)
D. Launslager
Selected clinical experience
Outcome of twin and triplet gestations in a Spanish center
449(6)
R. Porta
M. C. Cespedes
V. Molina
J. Ruiz
R. Aurell
J. M. Mallafre
J. Rios
Paying the costs in the NICU
455(4)
W. MacKendrick
Legal and ethical implications of triplet pregnancies: a lawyer's view
459(4)
V. Samuels
X Future directions 463(6)
Practical guidelines for the future
465(4)
I. Blickstein
L. G. Keith
Appendix: Sources of information on multiple births 469(6)
Index 475

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